May 30, 2023

Sydney Opera House at night

On my latest journey to Australia, I met with a handful of startups which are fixing onerous issues in healthcare, like mapping the mind, predicting seizures, and enhancing rehabilitation for aged sufferers. And in all of those instances, cloud applied sciences are serving to to speed up analysis and innovation.

After half a dozen journeys unfold throughout twenty years, huge is the primary phrase that involves thoughts once I consider Australia. From the Nice Barrier Reef to the Blue Mountains, all the best way to Kakadu Nationwide Park, it’s an immensely biodiverse place. House to greater than 1 million plant and animal species, many distinctive. Nonetheless, it’s a rustic that’s outlined as a lot by distance and the areas between, as it’s by pure magnificence. At almost the scale of the continental United States, Australia has lower than 1/tenth the inhabitants — however the inhabitants it does have is without doubt one of the most numerous on the earth, together with a wealthy mix of indigenous and immigrant cultures. It’s a rustic of fantastic contrasts. And for that purpose, it ought to come as no shock that the companies and concepts born in Australia are as numerous because the folks that inhabit it.

For a number of weeks in January and February, I had an opportunity to go to the east coast of Australia, which coincided with our first AWS Area launch of the New 12 months. After a fast go to to Rod Laver Area, the place I witnessed an unbelievable exhibiting from Novak Djokovic in opposition to Stefanos Tsitsipas, I spent most of my time assembly with AWS prospects and Amazonians which are inventing Australia into the longer term. From centuries-old banks and enormous telco enterprises, to younger startups doing all the things from sensible farming to piloting subterranean robots that map water techniques beneath the town streets of Melbourne, the cloud helps corporations of all sizes innovate shortly and at scale.

All of it begins with the mind

Australia is residence to a flourishing startup scene. It’s flush with corporations targeted on enhancing healthcare outcomes, not just for folks in Australia, however in every single place on the earth. And all of it begins with the mind.

Earlier this yr, after we launched the AWS Asia Pacific (Melbourne) Area, I wrote about Omniscient Neurotechnology (o8t). A company that has built brain mapping software with the potential to revolutionize not only neurosurgery, but the way that we diagnose and treat both neurological and mental health conditions. When I got to Sydney, they were kind enough to sit and chat about their technology stack, and how cloud services, specifically machine learning, allow them to produce personalized brain maps from existing MRIs that not only show how a patient’s brain is shaped, but how each and every connection is clustered. And while I declined a personal brain scan (I’m not quite ready to know everything that’s going on inside my head), I left our conversation feeling hopeful. I remember the days when MRIs were filed in cabinets, and analyzing hundreds of thousands of data points was a pipe dream. This technology truly has the potential to improve our collective understanding of the brain, accelerate research, and most importantly, improve the lives of patients. I first learned of Omniscient from Billion Dollar Napkin, and I’m together with a hyperlink to the episode as a result of it’s completely value watching.

It’s thrilling to see how new applied sciences are getting used to reinforce the experience of docs, researchers, and medical professionals. We are able to all agree that extra precision in neurosurgery is an efficient factor. Nonetheless, an space that’s typically neglected, however equally vital, is growing the instruments that present sufferers with extra management of their therapies.

Seer Medical is a startup targeted on enhancing the lives of individuals residing with epilepsy. They’ve created a non-invasive wearable gadget that can be utilized at residence to constantly accumulate EEG and ECG information from a affected person. The info is saved within the cloud (a whole bunch of TBs), then analyzed to detect coronary heart and brainwave abnormalities, that are used to foretell seizures earlier than they happen. Entry to such a data was traditionally restricted to multi-day research that relied on costly gear and required sufferers to remain at a clinic in a single day for commentary. When the research concluded, so did information assortment. What Seer has developed is a recreation changer for sufferers, in addition to docs and researchers. It provides sufferers autonomy. In the event that they know that some days are larger danger than others they will plan for it and reduce dangers. For docs and researchers it means extra and higher information to review, which can at some point assist them stop epileptic seizures altogether.

In each instances, cloud applied sciences paired with human intelligence are shifting us nearer to a future the place personalised healthcare is the usual, not the exception.

Organic intelligence

Not everyone studying the brain is focused on healthcare. Melbourne’s Cortical Labs are developing what they call “DishBrain Intelligence”. At the intersection of soft tissue and silicon, they are using stem cells to create the equivalent of a neural network that lives on a lab slide (the “DishBrain”).

Werner observing DishBrain computer on a lab slide
I have to admit, it’s been a while since I’ve donned a lab coat. Putting one on again at Cortical Labs really took me back.

So far, they have taught stem cells to play Pong. Just like the neural networks utilized in machine studying, these biologic computer systems depend on reinforcement studying. When an motion is carried out, the community is both rewarded or penalized based mostly on the outcome.

At a high-level, right here’s the way it works. The slide makes use of electrical inputs to see the paddle and ball, and electrical outputs to maneuver the paddle. When the ball makes contact with the paddle, the community is rewarded with a small quantity of targeted power. When the paddle misses the ball, the community is given a small quantity of random noise. Over time, the stem cells study to optimize the community to hit the ball. The irony is just not misplaced on me that we now have spent a long time designing techniques that mimic the human mind, and now we’re seeing neural stem cells utilized in natural computer systems. Joking apart, the research being done by Cortical Labs is intriguing, and reveals that there’s nonetheless loads that we now have to study. Within the close to future, they are going to be wanting into the impacts of medication and alcohol on their organic computer systems — it will likely be fascinating to see what they uncover.

Wholesome physique, wholesome thoughts… and a little bit of aggressive benefit

Transferring from the lab to the realm of on a regular basis actions, there are Australian startups doing fascinating work on the crossroads of well being and sport. Firms like VueMotion, who’re utilizing laptop imaginative and prescient to develop machine studying fashions that may monitor kinetic and kinematic information for athletes — all the things from joint angles and gait evaluation, to the affect drive of a foot strike or a tough minimize on the soccer pitch.

Just like how Omniscient are constructing personalised mind maps, VueMotion are creating personalised physique fashions. They confirmed me a demo of a runner whose stride lengths diverse from left to proper foot with an overlay of kinematic information. With such a data, trainers and coaches can shortly achieve an understanding of how somebody strikes in a pure setting, make changes, then monitor how their actions change over time — each progressions and regressions — all utilizing video captured from a smartphone.

What VueMotion has constructed has actual potential to stop accidents and enhance efficiency for athletes in any respect ranges. It’s the kind of innovation I alluded to in this year’s predictions. But the implications are much bigger than sport. VueMotion believes that their technology can also improve elder care and rehabilitation. Giving doctors and physical therapists the tools and data they need to draw insights, create patient specific plans, and track progress over time. It’s yet another example of technology augmenting expertise in healthcare.

Last, but certainly not least, are Bolt6. I met with them at the Australian Open, where they were running a proof of concept for player, racket, and ball tracking — processed and analyzed in the cloud (no server racks required). I first noticed how prevalent technology had become in tennis watching the US Open last summer. The entire line judges had been gone. Only a chair umpire and the ball crew. A product of the pandemic, however probably an indication of issues to return. This realization left me with extra questions than solutions. How correct had been the road calls? Would this alteration the notion of equity for gamers and followers? Wouldn’t it velocity up matches, and if sure, how would it not affect participant fatigue and incidence of damage?

The expertise Bolt6 has developed to make line calls may be very correct. With an error tolerance of three millimeters, it offers extra precision than the common line decide. And it’s constant — a digicam isn’t going to vary a name when a participant yells or smashes a racket.

With X, Y, Z monitoring, Bolt6 can do way more than make a line name or measure gait, they will do issues like decide how shut a participant is to a ball and the way they’re shaping as much as make successful, even assess fatigue in real-time. And their innovation doesn’t cease with tennis. Bolt6 can also be offering the expertise that permits NASCAR to trace each automobile on a monitor with 300 millisecond supply, no matter the place on the earth a race is going down. What they’ve constructed opens up a close to infinite variety of analytics that may enhance coaching and technique for all sports activities, and improve broadcasts for followers.

As I mentioned on the finish of final yr, the sports activities world is at present on the verge of the largest revolution it has ever seen, and cloud applied sciences are on the middle of this alteration.

It takes a village

I’m often requested questions on how issues work at Amazon. How we do issues. What drives innovation. Every little thing from writing docs to successfully managing giant engineering groups constructing distributed techniques. I can share processes, I can talk about tradition, however what makes Amazon work is the Amazonians. With out them, what you’ve examine on this put up wouldn’t be attainable.

A group picture with a few Amazonians from Down Under
Thanks to all the groups from Melbourne to Sydney that made this a really particular journey.

Till subsequent time

As huge and numerous as Australia may be, there was a standard theme shared by the businesses, entrepreneurs, and engineers I met with: a ardour to unravel onerous human issues. As I mirror on this journey, it’s really inspiring to see how cloud applied sciences are being harnessed to enhance healthcare outcomes. Now, as at all times, go construct!